In older patients, this is crucial to understand as polypharmacy is popular and will potentiate the chance of DDIs and ADRs. Thus, concurrent ingestion of CYP2D6 inhibitors or inducers could potentiate or block tramadol conversion into ODT and This might boost or minimize efficacy/ADRs from the prescribed tramadol. Literature https://alexf161six5.ourcodeblog.com/profile