Segmental involvement in PAD differs with the danger elements and metabolic comorbidities present in people. DM is definitely an independent predictor on the anatomical distribution of PAD. 11,13 In contrast, CKD normally triggers distal involvement in uremia via vascular calcification, which was shown to become attributable on the osteogenic differentiation https://www.sgvascularctr.com/treatment-of-peripheral-artery-disease-pad-in-singapore-a-comprehensive-guide/